Molecules Engineered Against Oncogenic Proteins and Cancer

Published in 2023 by Wiley, this monograph represents the culmination of decades of chemical research by Elias James Corey, a Nobel laureate in Chemistry. The book serves as a scholarly distillation of the author's work in synthetic organic chemistry, specifically focusing on the development of molecular entities designed to target and neutralize the proteins that drive oncogenic processes. It is situated within a long lineage of professional scientific literature intended for medicinal chemists, oncologists, and advanced researchers seeking to understand the mechanistic underpinnings of targeted cancer therapies.

The design and content of the volume reflect Corey's rigorous methodological approach to retrosynthetic analysis and molecular architecture. As an academic text, it avoids the stylistic trends of mass-market publishing, prioritizing structural diagrams, reaction schematics, and detailed biochemical pathways. The work was received by the scientific community as a definitive reference for modern drug discovery, highlighting the intersection of chemical synthesis and translational medicine by a figure widely considered one of the most influential chemists of the twentieth and twenty-first centuries.