Proteinligand Interactions

Published in 2012 by Wiley-VCH, Protein-Ligand Interactions was compiled to address the increasing need for a comprehensive reference on the physical and chemical principles governing biomolecular recognition. It was designed to bridge the gap between structural biology, computational chemistry, and medicinal chemistry, providing researchers with a structured overview of the methods used to predict and analyze how small molecules bind to protein targets.

The volume was edited by Holger Gohlke, a prominent researcher in the field of computational structural biology and molecular modeling. Gohlke focused the text on presenting a detailed scientific framework for understanding binding affinities, drawing on contributions from leading experts to synthesize theoretical models and experimental techniques. The work is widely regarded in academic circles as a rigorous technical resource for students and practitioners involved in drug discovery and molecular design.